Transcriptome, which can be expressed as the total RNA molecules produced by the genome of a cell, a tissue or an organism, is dynamic and under constant change due to the differences in gene expression. Studies in transcriptomics aims to examine the transcriptome using high-throughput technologies like microarrays and next generation sequencing. 

Transcriptome analysis is becoming increasingly important due to its ability to provide better understanding of how the changes in the expressions of genetic variants play a part in the development and progression of complex diseases such as cancer and diabetes.